Generation of TALEN-mediated GRdim knock-in rats by homologous recombination.

Transcription Activator-Like Effector Nucleases (TALEN) are potential tools for precise genome engineering of laboratory animals. We report the first targeted genomic integration in the rat using TALENs (Transcription Activator-Like Effector Nucleases) by homology-derived recombination (HDR). We ass...

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Detalles Bibliográficos

Principais autores:	Verónica Ponce de León, Anne-Marie Mérillat, Laurent Tesson, Ignacio Anegón, Edith Hummler
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Acceso en liña:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24523878/?tool=EBI
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