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L1CAM/CD171 expression in human tumors and its association with tumor phenotype

Background and purpose: L1CAM (CD171) is suggested to play a critical role in cancer. Because of its expression in only few normal tissues and its membranous nature, L1CAM is a promising drug target. Patient/material and methods: To clarify the role of L1CAM expression in different cancer types, a...

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Principais autores: Seyma Büyücek, Magalie Lurati, Katharina Möller, Florian Fiehweger, Ria Schlichter, Anne Menz, Andreas M Luebke, Viktor Reiswich, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Florian Lutz, Sören Weidemann, Frank Jacobsen, David Dum, Christian Bernreuther, Patrick Lebok, Guido Sauter, Andreas H. Marx, Ronald Simon, Christoph Fraune, Natalia Gorbokon, Eike Burandt, Sarah Minner, Stefan Steurer, Till S Clauditz, Till Krech, Viktoria Chirico, Maximilian Lennartz
Formato: Artigo
Idioma:Inglês
Publicado em: Medical Journals Sweden 2025-12-01
Colecção:Acta Oncologica
Assuntos:
L1CAM
cell adhesion molecules
biomarkers
tumor
membrane proteins
tissue array analysis
Acesso em linha:https://medicaljournalssweden.se/actaoncologica/article/view/43587
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