Loss of osteoprotegerin expression in the inner ear causes degeneration of the cochlear nerve and sensorineural hearing loss

Osteoprotegerin (OPG) is a key regulator of bone remodeling. Mutations and variations in the OPG gene cause many human diseases that are characterized by not only skeletal abnormalities but also poorly understood hearing loss: Paget's disease, osteoporosis, and celiac disease. To gain insight into t...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Shyan-Yuan Kao, Judith S. Kempfle, Jane B. Jensen, Deborah Perez-Fernandez, Andrew C. Lysaght, Albert S. Edge, Konstantina M. Stankovic
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2013-08-01
Цуврал:	Neurobiology of Disease
Нөхцлүүд:	Osteoprotegerin Spiral ganglion cells Cochlear neurons Sensorineural hearing loss Auditory stem cell
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0969996113001228
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!