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ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys.

Previous studies with a number of selective acylcoenzyme A:cholesterol acyltransferase (ACAT) inhibitors in several animal models have demonstrated significant reductions in plasma cholesterol and, in some studies, triglyceride levels. This study was conducted to examine the effects of two ACAT inhi...

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Detalhes bibliográficos
Principais autores: S.M. Wrenn, Jr, J.S. Parks, F.W. Immermann, L.L. Rudel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 1995-06-01
coleção:Journal of Lipid Research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227520411289
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