Assessing differential application of thromboprophylaxis regimes related to risk of pulmonary embolism and mortality in COVID-19 patients through instrumental variable analysis

Abstract Thrombotic complications are common in Coronavirus disease 2019 (COVID-19) patients, with pulmonary embolism (PE) being the most frequent. Randomised trials have provided inconclusive results on the optimal dosage of thromboprophylaxis in critically ill COVID-19 patients. We utilized data f...

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Principais autores:	Linda Nab, Chantal Visser, Bas C. T. van Bussel, Albertus Beishuizen, Remy H. H. Bemelmans, Hugo ten Cate, F. Nanne Croles, Coen van Guldener, C. Peter C. de Jager, Menno V. Huisman, Marten. R. Nijziel, Pieter W. Kamphuisen, Frederikus A. Klok, Stephanie C. E. Koster, Nuray Kuşadasi, Karina Meijer, Corstiaan A. den Uil, Roger E. G. Schutgens, Frank Stam, Alexander P. J. Vlaar, Eline A. Vlot, Marijke P. M. Linschoten, Folkert W. Asselbergs, Marieke J. H. A. Kruip, Saskia le Cessie, Suzanne C. Cannegieter, Dutch Covid and Thrombosis Coalition & the CAPACITY-COVID collaborative consortium
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-03-01
coleção:	Scientific Reports
Assuntos:	COVID-19 Heparin Low-molecular-weight Pulmonary embolism Hospital mortality Dose–response relationship
Acesso em linha:	https://doi.org/10.1038/s41598-024-77858-w
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