Transcription factor clusters regulate genes in eukaryotic cells

Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear. Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged...

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Bibliographic Details

Main Authors:	Adam JM Wollman, Sviatlana Shashkova, Erik G Hedlund, Rosmarie Friemann, Stefan Hohmann, Mark C Leake
Format:	Artigo
Language:	Inglês
Published:	eLife Sciences Publications Ltd 2017-08-01
Series:	eLife
Subjects:	gene expression transcription factors single-molecule super-resolution cell signaling
Online Access:	https://elifesciences.org/articles/27451
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