Comprehensive Investigation of Polymorphic Stability and Phase Transformation Kinetics in Tegoprazan

<b>Background/Objectives:</b> Tegoprazan (TPZ) is a potassium-competitive acid blocker (P-CAB) used to treat conditions such as gastroesophageal reflux disease, peptic ulcer, and <i>Helicobacter pylori</i> infection. It exists in three solid forms: amorphous, Polymorph A, and Polymorph B. This study...

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Hlavní autoři:	Joo Ho Lee, Ki Hyun Kim, Se Ah Ryu, Jason Kim, Kiwon Jung, Ki Sung Kang, Tokutaro Yamaguchi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-07-01
Edice:	Pharmaceutics
Témata:	Tegoprazan polymorphism disappearing polymorph solvent-mediated phase transformation (SMPT) conformational analysis KJMA equation
On-line přístup:	https://www.mdpi.com/1999-4923/17/7/928
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