Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition

Heat shock protein 70 (Hsp70) is widely involved in immune disorders, making it as an attractive drug target for inflammation diseases. Nonselective induction of Hsp70 upregulation for inflammation therapy could cause extensive interference in inflammation-unrelated protein functions, potentially re...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Li-Chao Wang, Li-Xi Liao, Hai-Ning Lv, Dan Liu, Wei Dong, Jian Zhu, Jin-Feng Chen, Meng-Ling Shi, Ge Fu, Xiao-Min Song, Yong Jiang, Ke-Wu Zeng, Peng-Fei Tu
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2017-09-01
Rangatū:	EBioMedicine
Ngā marau:	Heat shock protein 70 (Hsp70) Handelin Drug target Covalent modification Neuroinflammation
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2352396417303286
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!