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Piscidin is Highly Active against Carbapenem-Resistant Acinetobacter baumannii and NDM-1-Producing Klebsiella pneumonia in a Systemic Septicaemia Infection Mouse Model

This study was designed to investigate the antimicrobial activity of two synthetic antimicrobial peptides from an aquatic organism, tilapia piscidin 3 (TP3) and tilapia piscidin 4 (TP4), in vitro and in a murine sepsis model, as compared with ampicillin, tigecycline, and imipenem. Mice were infected...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Chieh-Yu Pan, Jian-Chyi Chen, Te-Li Chen, Jen-Leih Wu, Cho-Fat Hui, Jyh-Yih Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2015-04-01
Schriftenreihe:Marine Drugs
Schlagworte:
antimicrobial peptide
piscidin
Acinetobacter baumannii
Klebsiella pneumonia
Online-Zugang:http://www.mdpi.com/1660-3397/13/4/2287
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