Overexpressed HDAC8 in cervical cancer cells shows functional redundancy of tubulin deacetylation with HDAC6

Abstract Background Histone deacetylases (HDACs) are involved in epigenetic gene regulation via deacetylation of acetylated lysine residues of both histone and non-histone proteins. Among the 18 HDACs identified in humans, HDAC8, a class I HDAC, is best understood structurally and enzymatically. How...

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Principais autores:	G. R. Vanaja, Hemalatha Golaconda Ramulu, Arunasree M. Kalle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-05-01
coleção:	Cell Communication and Signaling
Assuntos:	HDAC8 Alpha tubulin Tubulin deacetylase HDAC6 Cervical cancer
Acesso em linha:	http://link.springer.com/article/10.1186/s12964-018-0231-4
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