Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.

The ApoE ε4 allele is the most significant genetic risk factor for late-onset Alzheimer disease. The risk conferred by ε4, however, differs across populations, with populations of African ancestry showing lower ε4 risk compared to those of European or Asian ancestry. The cause of this heterogeneity...

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Detaylı Bibliyografya
Asıl Yazarlar:	Farid Rajabli, Briseida E Feliciano, Katrina Celis, Kara L Hamilton-Nelson, Patrice L Whitehead, Larry D Adams, Parker L Bussies, Clara P Manrique, Alejandra Rodriguez, Vanessa Rodriguez, Takiyah Starks, Grace E Byfield, Carolina B Sierra Lopez, Jacob L McCauley, Heriberto Acosta, Angel Chinea, Brian W Kunkle, Christiane Reitz, Lindsay A Farrer, Gerard D Schellenberg, Badri N Vardarajan, Jeffery M Vance, Michael L Cuccaro, Eden R Martin, Jonathan L Haines, Goldie S Byrd, Gary W Beecham, Margaret A Pericak-Vance
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Public Library of Science (PLoS) 2018-12-01
Seri Bilgileri:	PLoS Genetics
Online Erişim:	https://doi.org/10.1371/journal.pgen.1007791
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.

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