Antipsychotic use in bipolar disorder: clinical and genomic correlates– a Mayo clinic bipolar disorder biobank study

Abstract Background Responsiveness to mood-stabilizing pharmacotherapy varies in bipolar disorder (BD). We investigated clinical correlates of second-generation antipsychotic (SGA) treatment response and conducted the first genome-wide association study (GWAS), including exploratory polygenic scores...

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Main Authors:	Balwinder Singh, Ada Man-Choi Ho, Brandon J. Coombes, Francisco Romo-Nava, David J. Bond, Marin Veldic, Richard S. Pendegraft, Anthony Batzler, Alfredo B. Cuellar-Barboza, Manuel Gardea-Reséndez, Miguel L. Prieto, Aysegul Ozerdem, Susan L. McElroy, Joanna M. Biernacka, Mark A. Frye
Format:	Artigo
Language:	Inglês
Published:	SpringerOpen 2025-12-01
Series:	International Journal of Bipolar Disorders
Subjects:	Bipolar disorder Antipsychotics Treatment response Pharmacogenomics
Online Access:	https://doi.org/10.1186/s40345-025-00405-7
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