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Efficacy of Emu Oil Transfersomes for Local Transdermal Delivery of 4-OH Tamoxifen in the Treatment of Breast Cancer

Oral tamoxifen used in the prevention and treatment of ductal carcinoma in situ (DCIS) (estrogen-positive) patients has limited acceptance, due to its adverse side effects. The efficacy of tamoxifen is related to its major metabolite, 4-hydroxytamoxifen. Local transdermal therapy of 4-hydroxytamoxif...

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Principais autores: Usha Sundralingam, Srikumar Chakravarthi, Ammu Kutty Radhakrishnan, Saravanan Muniyandy, Uma D. Palanisamy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
coleção:Pharmaceutics
Assuntos:
local transdermal therapy
tamoxifen
4-hydroxytamoxifen
DCIS
emu oil
Acesso em linha:https://www.mdpi.com/1999-4923/12/9/807
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