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Molecular mechanism of calcium induced trimerization of C1q-like domain of otolin-1 from human and zebrafish

Abstract The C1q superfamily includes proteins involved in innate immunity, insulin sensitivity, biomineralization and more. Among these proteins is otolin-1, which is a collagen-like protein that forms a scaffold for the biomineralization of inner ear stones in vertebrates. The globular C1q-like do...

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Auteurs principaux: Rafał Hołubowicz, Andrzej Ożyhar, Piotr Dobryszycki
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2021-06-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-021-92129-8
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