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Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p.

Intron-containing pre-mRNAs are normally retained and processed in the nucleus but are sometimes exported to the cytoplasm and degraded by the nonsense-mediated mRNA decay (NMD) pathway as a consequence of their inclusion of intronic in-frame termination codons. When shunted to the cytoplasm by auto...

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Bibliográfalaš dieđut
Váldodahkkit: Shuyun Dong, Allan Jacobson, Feng He
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2010-04-01
Ráidu:PLoS Biology
Liŋkkat:http://europepmc.org/articles/PMC2864733?pdf=render
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