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Uncovering shared and tissue-specific molecular adaptations to intermittent fasting in liver, brain, and muscle

Intermittent fasting (IF) has emerged as a powerful dietary intervention with profound metabolic benefits, yet the tissue-specific molecular mechanisms underlying these effects remain poorly understood. In this study, we employed comprehensive proteomics and transcriptomics analysis to investigate t...

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Huvudupphov: Yibo Fan, Senuri De Silva, Nishat I Tabassum, Xiangyuan Peng, Vernise JT Lim, Xiangru Cheng, Keshava K Datta, Rohan Lowe, Terrance G Johns, Mark P Mattson, Suresh Mathivanan, Christopher G Sobey, Eitan Okun, Yong U Liu, Guobing Chen, Mitchell Kim Peng Lai, Dong-Gyu Jo, Jayantha Gunaratne, Thiruma V Arumugam
Materialtyp: Artigo
Språk:Inglês
Utgiven: eLife Sciences Publications Ltd 2026-04-01
Serie:eLife
Ämnen:
intermittent fasting
proteomics
transcriptomics
metabolic reprogramming
Serpin A1c
bioinformatics
Länkar:https://elifesciences.org/articles/107332
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