DNA Damage Response Evaluation Provides Novel Insights for Personalized Immunotherapy in Glioma

BackgroundDNA damage response (DDR) proficiency is the principal mechanism of temozolomide (TMZ) resistance in glioma. Accumulating evidence has also suggested the determining role of DDR in anticancer immunity. We propose that a comprehensive investigation of the DDR landscape can optimize glioma t...

Full description

Bibliographic Details

Main Authors:	Mu Chen, Bingsong Huang, Lei Zhu, Qi Wang, Ying Pang, Meng Cheng, Hao Lian, Min Liu, Kaijun Zhao, Siyi Xu, Jing Zhang, Chunlong Zhong
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2022-05-01
Series:	Frontiers in Immunology
Subjects:	DNA damage response immunotherapy glioma tumor microenvironment immune checkpoint blockade DNA repair
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.875648/full
Tags:	Add Tag No Tags, Be the first to tag this record!