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Phenotypic drug resistance and genome sequencing based identified mutations linked to resistance in Mycobacterium tuberculosis isolated from extrapulmonary clinical specimens

Abstract Globally, drug-resistant tuberculosis (DR-TB) is responsible for 13% of mortality attributable to antimicrobial resistance. In Ethiopia, extrapulmonary tuberculosis (EPTB) is a significant public health challenge, and drug resistance (DR) in EPTB is often overlooked. In a cross-sectional st...

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Wedi'i Gadw mewn:
Prif Awduron: Hilina Mollalign, Dawit Hailu Alemayehu, Kalkidan Melaku, Abaysew Ayele, Dawit Chala, Getu Diriba, Bazezew Yenew, Muluwork Getahun, Bethlehem Adnew, Shewki Moga, Jeffrey Michael Collins, Arash Ghodousi, Dereje Beyene, Kidist Bobosha, Liya Wassie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2026-02-01
Cyfres:Scientific Reports
Pynciau:
Extrapulmonary tuberculosis
Whole genome sequencing
Ethiopia
Compensatory mutation
Mynediad Ar-lein:https://doi.org/10.1038/s41598-026-40253-8
Tagiau: Ychwanegu Tag
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