The Role of IRF8 Polymorphisms in Systemic Sclerosis Development and Pathogenesis

Systemic sclerosis (SSc) is a rare autoimmune disease whose molecular mechanisms are not yet fully understood. There is no definitive cure, and the main causes of death are pulmonary fibrosis and pulmonary arterial hypertension. Here, we focus on the interferon regulators factor 8 (IRF8), a factor i...

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Autores principales:	Anna Mennella, Giuseppe Ocone, Katia Stefanantoni, Loredana Frasca
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-03-01
Colección:	Journal of Molecular Pathology
Materias:	systemic sclerosis (SSc) interferon regulatory factor 8 (IRF8) diffuse cutaneous (dcSSc) limited cutaneous (lcSSc) interferon-I (INF-I) single nucleotide polymorphism (SNPs)
Acceso en línea:	https://www.mdpi.com/2673-5261/5/1/8
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