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Case report: Therapeutic drug monitoring and CYP2D6 phenoconversion in a protracted paroxetine intoxication

ObjectiveThe cytochrome P450 2D6 (CYP2D6) is an enzyme involved in the oxidative biotransformation of various widely used drugs, including paroxetine, a substrate and strong inhibitor of the enzyme. The aim is to report on a case of protracted intoxication with paroxetine after a single overdose in...

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主要な著者: Alena Damborská, Lenka Hanáková, Eva Pindurová, Kateřina Horská
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2024-09-01
シリーズ:Frontiers in Pharmacology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2024.1444857/full
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