Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction

Background: Reactive oxygen species (ROS), predominantly generated by mitochondria, play a crucial role in the pathogenesis of intervertebral disc degeneration (IVDD). Reduction of ROS levels may be an effective strategy to delay IVDD. In this study, we assessed whether umbilical cord mesenchymal st...

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Detalhes bibliográficos

Principais autores:	Shu Jia, Tao Yang, Sheng Gao, Luyue Bai, Zhiguo Zhu, Siqi Zhao, Yexin Wang, Xiao Liang, Yanpeng Li, Longfei Gao, Zifang Zhang, Xu Gao, Dongru Li, Shang Chen, Bin Zhang, Chunyang Meng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-05-01
coleção:	Journal of Orthopaedic Translation
Assuntos:	Umbilical cord mesenchymal stem cells Exosomes Mitochondrion Intervertebral disc degeneration
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2214031X23000785
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