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Effect of a bacterial glutaminyl cyclase inhibitor on multi-species-biofilms

IntroductionModifying bacterial virulence could be an interesting alternative to antibiotics. The study aimed to examine the effects of an inhibitor targeting bacterial glutaminyl cyclase [which is selectively present in Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), and Prevotella interm...

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Principais autores: Sigrun Eick, Nadine Taudte, Daniel Ramsbeck, Anna Magdoń, Anton Sculean, Jan Potempa, Mirko Buchholz
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-12-01
Serier:Frontiers in Oral Health
Fag:
modifying bacterial virulence
Porphyromonas gingivalis
alternatives antibiotics
biofilm modulation
periodontitis
Online adgang:https://www.frontiersin.org/articles/10.3389/froh.2025.1716625/full
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