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Therapeutic implications for sphingolipid metabolism in metabolic dysfunction-associated steatohepatitis

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), a leading cause of chronic liver disease, has increased worldwide along with the epidemics of obesity and related dysmetabolic conditions characterized by impaired glucose metabolism and insulin signaling, such as ty...

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Principais autores: Bruno Ramos-Molina, Joana Rossell, Alejandra Pérez-Montes de Oca, Eva Pardina, Idoia Genua, Marina I. Rojo-López, María Teresa Julián, Núria Alonso, Josep Julve, Didac Mauricio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-06-01
coleção:Frontiers in Endocrinology
Assuntos:
steatotic liver
hepatic fibrosis
steatohepatitis
sphingolipids
inflammation
lipotoxicity
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2024.1400961/full
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