Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

ABSTRACT Although direct biological factors underlying the progression of Glioblastoma (GBM), an aggressive form of brain cancer, have been extensively studied, emerging evidence suggests that indirect biological triggers, such as traumatic brain injury (TBI), may also have a role. Since proteoglyca...

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Detalhes bibliográficos

Principais autores:	Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-04-01
coleção:	Advanced Science
Assuntos:	activated astrocytes cancer phenotype mechanobiology MMP‐2 p53 senescence
Acesso em linha:	https://doi.org/10.1002/advs.202509362
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