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BBIQ, a pure TLR7 agonist, is an effective influenza vaccine adjuvant

Better adjuvants are needed for vaccines against seasonal influenza. TLR7 agonists are potent activators of innate immune responses and thereby may be promising adjuvants. Among the imidazoquinoline compounds, 1-benzyl-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine (BBIQ) was reported to be a highly acti...

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Kaydedildi:
Asıl Yazarlar: Deepender Kaushik, Simran Dhingra, Madhuri T. Patil, Sakshi Piplani, Varun Khanna, Yoshikazu Honda-Okubo, Lei Li, Johnson Fung, Isaac G. Sakala, Deepak B. Salunke, Nikolai Petrovsky
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2020-08-01
Seri Bilgileri:Human Vaccines & Immunotherapeutics
Konular:
imidazoquinoline
tlr7
tlr8
imiquimod
vaccine
adjuvant
influenza
in-silico modeling
Online Erişim:http://dx.doi.org/10.1080/21645515.2019.1710409
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