Enhanced CTLA‐4 blockade anti‐tumor immunity with APG‐157 combination in a murine head and neck cancer

Abstract Background A phase I clinical study for patients with locally advanced H&N cancer with a new class of botanical drug APG‐157 provided hints of potential synergy with immunotherapy. We sought to evaluate the efficacy of the combination of APG‐157 and immune checkpoint inhibitors. Methods CCL...

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Detalhes bibliográficos

Principais autores:	Daniel Sanghoon Shin, Saroj Basak, Mysore S. Veena, Begoña Comin‐Anduix, Arjun Bhattacharya, Tien S. Dong, Albert Ko, Philip Han, Jonathan Jacobs, Neda A. Moatamed, Luis Avila, Matteo Pellegrini, Marilene Wang, Eri S. Srivatsan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-05-01
coleção:	Cancer Medicine
Assuntos:	APG‐157 head and neck cancer immune checkpoint inhibitors microbiome tumor microenvironment
Acesso em linha:	https://doi.org/10.1002/cam4.7212
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