The Design and Synthesis of a New Series of 1,2,3-Triazole-Cored Structures Tethering Aryl Urea and Their Highly Selective Cytotoxicity toward HepG2

Target cancer drug therapy is an alternative treatment for advanced hepatocellular carcinoma (HCC) patients. However, the treatment using approved targeted drugs has encountered a number of limitations, including the poor pharmacological properties of drugs, therapy efficiency, adverse effects, and...

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Bibliografski detalji

Glavni autori:	Sittisak Oekchuae, Jitnapa Sirirak, Purin Charoensuksai, Pawaris Wongprayoon, Natthaya Chuaypen, Jutatip Boonsombat, Somsak Ruchirawat, Pisit Tangkijvanich, Apichart Suksamrarn, Panupun Limpachayaporn
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-04-01
Serija:	Pharmaceuticals
Teme:	sorafenib analog 1,2,3-triazole-containing drug click reaction selective anti-HepG2 agent targeted cancer drug hepatocellular carcinoma (HCC)
Online pristup:	https://www.mdpi.com/1424-8247/15/5/504
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