Structure and Characterization of a Covalent Inhibitor of Src Kinase
Unregulated Src activity promotes malignant processes in cancer, but no Src-directed targeted therapies are used clinically, possibly because early Src inhibitors produce off-target effects leading to toxicity. Improved selective Src inhibitors may enable Src-directed therapies. Previously, we repor...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020-05-01
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| Collection: | Frontiers in Molecular Biosciences |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/article/10.3389/fmolb.2020.00081/full |
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