Spatial transcriptomic landscape and cellular neighborhood heterogeneity in cervical cancer: integrative single-cell and spatial RNA sequencing analysis

Abstract Background Cervical cancer ranks as the fourth most common malignancy among women worldwide, with approximately 604,000 new cases and 342,000 deaths annually. Despite advances in HPV vaccination and screening programs, significant challenges remain in diagnostic accuracy, therapeutic effica...

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Auteurs principaux:	Dieyi Mo, Huana Cao, Shaojuan Lai, Jinding Luo, Weijie Ye
Format:	Artigo
Langue:	Inglês
Publié:	Springer 2025-11-01
Collection:	Discover Oncology
Sujets:	Spatial transcriptomics Single-cell RNA sequencing Cervical cancer Tumor microenvironment Cellular neighborhoods Gene expression heterogeneity
Accès en ligne:	https://doi.org/10.1007/s12672-025-03788-2
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