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Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics

Abstract Condition‐dependent genetic interactions can reveal functional relationships between genes that are not evident under standard culture conditions. State‐of‐the‐art yeast genetic interaction mapping, which relies on robotic manipulation of arrays of double‐mutant strains, does not scale read...

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Автори: J Javier Díaz‐Mejía, Albi Celaj, Joseph C Mellor, Atina Coté, Attila Balint, Brandon Ho, Pritpal Bansal, Fatemeh Shaeri, Marinella Gebbia, Jochen Weile, Marta Verby, Anna Karkhanina, YiFan Zhang, Cassandra Wong, Justin Rich, D'Arcy Prendergast, Gaurav Gupta, Sedide Öztürk, Daniel Durocher, Grant W Brown, Frederick P Roth
Формат: Artigo
Мова:Inglês
Опубліковано: Springer Nature 2018-05-01
Серія:Molecular Systems Biology
Предмети:
condition‐dependent
DNA barcode
en masse
genetic interaction
sequencing
Онлайн доступ:https://doi.org/10.15252/msb.20177985
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