Differential roles of RIG-I like receptors in SARS-CoV-2 infection

Abstract Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5) sense viral RNA and activate antiviral immune responses. Herein we investigate their functions in human epithelial cells, the primary and initial target of severe acute respiratory syndrome coron...

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Hlavní autoři:	Duo-Meng Yang, Ting-Ting Geng, Andrew G. Harrison, Peng-Hua Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	KeAi Communications Co., Ltd. 2021-09-01
Edice:	Military Medical Research
Témata:	SARS-CoV-2 Pathogen pattern recognition receptor Melanoma differentiation-associated protein 5 Retinoic acid-inducible gene I
On-line přístup:	https://doi.org/10.1186/s40779-021-00340-5
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