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Polydatin attenuated neuropathic pain and motor dysfunction following spinal cord injury in rats by employing its anti-inflammatory and antioxidant effects

BackgroundConsidering the complex pathological mechanisms behind spinal cord injury (SCI) and the adverse effects of present non-approved drugs against SCI, new studies are needed to introduce novel multi-target active ingredients with higher efficacy and lower side effects. Polydatin (PLD) is a nat...

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Principais autores: Faezeh Sadat Bagheri Bavandpouri, Atefeh Azizi, Fatemeh Abbaszadeh, Amir Kiani, Mohammad Hosein Farzaei, Ehsan Mohammadi-Noori, Sajad Fakhri, Javier Echeverría
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-08-01
Serier:Frontiers in Pharmacology
Fag:
spinal cord injury
polydatin
oxidative stress
inflammation
motor activity
neuropathic pain
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1452989/full
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