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Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.

High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases. Total IgE is a strongly heritable trait. In a genome-wide associatio...

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Автори: Stephan Weidinger, Christian Gieger, Elke Rodriguez, Hansjörg Baurecht, Martin Mempel, Norman Klopp, Henning Gohlke, Stefan Wagenpfeil, Markus Ollert, Johannes Ring, Heidrun Behrendt, Joachim Heinrich, Natalija Novak, Thomas Bieber, Ursula Krämer, Dietrich Berdel, Andrea von Berg, Carl Peter Bauer, Olf Herbarth, Sibylle Koletzko, Holger Prokisch, Divya Mehta, Thomas Meitinger, Martin Depner, Erika von Mutius, Liming Liang, Miriam Moffatt, William Cookson, Michael Kabesch, H-Erich Wichmann, Thomas Illig
Формат: Artigo
Мова:Inglês
Опубліковано: Public Library of Science (PLoS) 2008-08-01
Серія:PLoS Genetics
Онлайн доступ:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000166&type=printable
Теги: Додати тег
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