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Defining key design elements of registry-based randomised controlled trials: a scoping review

Abstract Background Traditional randomised controlled trials remain the gold standard for improving clinical care but they do have their limitations, including their associated high costs, high failure rate and limited external validity. An alternative methodology is the newly defined, prospective,...

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Principais autores: Bill Karanatsios, Khic-Houy Prang, Ebony Verbunt, Justin M. Yeung, Margaret Kelaher, Peter Gibbs
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:Trials
Fag:
Registry trials
Pragmatic trials
Real-world evidence
Registry
Online adgang:http://link.springer.com/article/10.1186/s13063-020-04459-z
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