Integrated bioinformatics reveals tubulointerstitial immune microenvironment signatures and machine learning-driven prognostication of clinical treatment response in lupus nephritis

Lupus nephritis (LN) represents the most severe renal manifestation of systemic lupus erythematosus (SLE), contributing to significant morbidity. While current assessments focus on glomerular pathology, tubulointerstitial lesions may offer critical insights into disease progression and treatment res...

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Principais autores:	Jialong Ke, Guanghong Gu, Wenpeng Ni, Jialin He, Zhouyu Zeng, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Nan Tan, Chilun Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis Group 2026-12-01
Series:	Autoimmunity
Assuntos:	Lupus nephritis clinical treatment response least absolute shrinkage and selection operator nomogram immune infiltration
Acceso en liña:	https://www.tandfonline.com/doi/10.1080/08916934.2026.2652037
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