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NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer

Abstract Background The accurate screening of tumor genomic landscapes for somatic mutations using high-throughput sequencing involves a crucial step in precise clinical diagnosis and targeted therapy. However, the complex inherent features of cancer tissue, especially, tumor genetic intra-heterogen...

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主要な著者: Irantzu Anzar, Angelina Sverchkova, Richard Stratford, Trevor Clancy
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2019-05-01
シリーズ:BMC Medical Genomics
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オンライン・アクセス:http://link.springer.com/article/10.1186/s12920-019-0508-5
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