Csk-mediated Src family kinase regulation dampens neutrophil infiltration during pulmonary infection

Neutrophil recruitment is crucial for pathogen elimination. However, precise control of the inflammatory response prevents overshooting reactions. Neutrophil activation initiates signaling, resulting in integrin β2 (Itgb2) activation and neutrophil arrest. Src family kinases are involved in multiple...

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Autori principali:	Wida Amini, Lena Schemmelmann, Jan-Niklas Heming, Marina Oguama, Katharina Thomas, Helena Block, Pia Lindental, Bernadette Bardel, Andreas Margraf, Oliver Soehnlein, Anika Cappenberg, Alexander Zarbock
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical investigation 2025-07-01
Serie:	JCI Insight
Soggetti:	Immunology Inflammation
Accesso online:	https://doi.org/10.1172/jci.insight.188323
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