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Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson’s Disease via Lysophosphatidic Acid Receptors

Gintonin is a ginseng-derived lysophosphatidic acid receptor (LPAR) ligand. Although previous in vitro and in vivo studies demonstrated the therapeutic role of gintonin against Alzheimer’s disease, the neuroprotective effects of gintonin in Parkinson’s disease (PD) are still unknown. We investigated...

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Autori principali: Jong Hee Choi, Minhee Jang, Seikwan Oh, Seung-Yeol Nah, Ik-Hyun Cho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018-05-01
Serie:Frontiers in Pharmacology
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Accesso online:https://www.frontiersin.org/article/10.3389/fphar.2018.00515/full
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