Do Cenobamate Pharmacokinetics Change with Co-Administered Antiseizure Medications? An Exploratory Analysis of Responder Patients with Focal Drug-Resistant Epilepsy

<b>Background:</b> Cenobamate (CNB) is an anti-seizure medication (ASM) approved for the treatment of drug-resistant focal epilepsy in adults. Notwithstanding significant proof of efficacy, real-world pharmacokinetics (PK) data are lacking, particularly regarding sex-based variations and the effect...

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Detalhes bibliográficos

Principais autores:	Bruno Charlier, Viviana Izzo, Giovanni Assenza, Anna Chiara Balsamo, Flavia Cirillo, Albino Coglianese, Carlo Di Bonaventura, Mariana Fernandes, Antonio Gambardella, Emanuele Cerulli Irelli, Claudio Liguori, Sandra Rufolo, Ilaria Sammarra, Amelia Filippelli, Francesca Felicia Operto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-01-01
coleção:	Pharmaceutics
Assuntos:	cenobamate antiseizure medication pharmacokinetics therapeutic drug monitoring
Acesso em linha:	https://www.mdpi.com/1999-4923/18/1/92
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