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A high throughput drug screening paradigm using transgenic Caenorhabditis elegans model of Alzheimer’s disease

Alzheimer’s disease (AD), characterized by memory loss and cognitive decline, is one of the diseases with the highest attrition rate in drug development. As with other neurodegenerative diseases, AD manifests on several scales (molecular, cellular and organismal), resulting in an organismal phenotyp...

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Autors principals: Emelyne Teo, Soon Yew John Lim, Sheng Fong, Anis Larbi, Graham D. Wright, Nicholas Tolwinski, Jan Gruber
Format: Artigo
Idioma:Inglês
Publicat: KeAi Communications Co., Ltd. 2020-01-01
Col·lecció:Translational Medicine of Aging
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2468501119300501
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