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Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery.

The introduction ten years ago of RNA interference (RNAi) as a tool for molecular exploration in Trypanosoma brucei has led to a surge in our understanding of the pathogenesis and biology of this human parasite. In particular, a genome-wide RNAi screen has recently been combined with next-generation...

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Autori principali: Rebecca L Barnes, Huafang Shi, Nikolay G Kolev, Christian Tschudi, Elisabetta Ullu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS Pathogens
Accesso online:http://europepmc.org/articles/PMC3359990?pdf=render
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