EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes.

Mitochondrial dysfunction, caspase activation and caspase-dependent DNA fragmentation are involved in cell damage in many tissues. However, differentiated cardiomyocytes repress the expression of the canonical apoptotic pathway and their death during ischemia is caspase-independent. The atypical BH3...

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Bibliografische Detailangaben

Hauptverfasser:	Jisheng Zhang, Junmei Ye, Albert Altafaj, Maria Cardona, Núria Bahi, Marta Llovera, Xavier Cañas, Stuart A Cook, Joan X Comella, Daniel Sanchis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2011-03-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://doi.org/10.1371/journal.pone.0017998
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