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4-Hydroxynonenal (HNE) and hepatic injury related to chronic oxidative stress

4-Hydroxynonenal (HNE), a major end-product of free-radical activated peroxidation of polyunsaturated fatty acids, has attracted great scientific interest. HNE is more stable than free radicals and can diffuse within the cell or leave it and react with targets far from the initial site. These reacti...

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Principais autores: Ganka Bekyarova, Maria Tzaneva, Kamelia Bratoeva, Irina Ivanova, Andrei Kotzev, Minka Hristova, Dimo Krastev, Ivan Kindekov, Milka Mileva
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2019-01-01
Serier:Biotechnology & Biotechnological Equipment
Fag:
4-hydroxynonenal
signalling pathway
mitochondrial dysfunction
apoptosis
liver injury
non-alcoholic fatty liver disease
Online adgang:http://dx.doi.org/10.1080/13102818.2019.1674690
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