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Virtual Screening and Bioactivity Evaluation of Novel Androgen Receptor Antagonists From Anti-PCa Traditional Chinese Medicine Prescriptions

Prostate cancer (PCa), a type of malignancy that arises in the prostate gland, is the most commonly diagnosed neoplasm and the second leading cause of cancer-related deaths in men. Acquisition of resistance to conventional therapy is a major problem for PCa patient treatment. Androgen receptor (AR)...

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Autors principals: Wenya Han, Yuqi Shi, Jie Su, Zhennan Zhao, Xin Wang, Jiazhong Li, Huanxiang Liu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020-09-01
Col·lecció:Frontiers in Chemistry
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Accés en línia:https://www.frontiersin.org/article/10.3389/fchem.2020.582861/full
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