Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function

The HRAS gene plays a crucial role in regulating essential cellular processes for life, and this gene's misregulation is linked to the development of various types of cancers. Nonsynonymous single nucleotide polymorphisms (nsSNPs) within the coding region of HRAS can cause detrimental mutations that...

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Detalles Bibliográficos

Principais autores:	Sadaqat Ali, Usman Ali, Adeem Qamar, Imran Zafar, Muhammad Yaqoob, Qurat ul Ain, Summya Rashid, Rohit Sharma, Hiba-Allah Nafidi, Yousef A. Bin Jardan, Mohammed Bourhia
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Chemistry
Assuntos:	cancer genetic variants mutations oncogenic signaling pathways SNPs nsSNP
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fchem.2023.1173624/full
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