The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle

Myostatin inhibition therapy has held much promise for the treatment of muscle wasting disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD). Following on from promising pre-clinical data in dystrophin-deficient mice and dogs, several clinical trials were ini...

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Päätekijät:	Emma Rybalka, Cara A. Timpani, Danielle A. Debruin, Ryan M. Bagaric, Dean G. Campelj, Alan Hayes
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2020-12-01
Sarja:	Cells
Aiheet:	myostatin inhibition Duchenne Muscular Dystrophy skeletal muscle muscle development clinical trials translation
Linkit:	https://www.mdpi.com/2073-4409/9/12/2657
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