HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.

<h4>Background</h4>Hypoxia plays a key role in ischaemic and neovascular disorders of the retina. Cellular responses to oxygen are mediated by hypoxia-inducible transcription factors (HIFs) that are stabilised in hypoxia and induce the expression of a diverse range of genes. The purpose of this stud...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Freya M Mowat, Ulrich F O Luhmann, Alexander J Smith, Clemens Lange, Yanai Duran, Sarah Harten, Deepa Shukla, Patrick H Maxwell, Robin R Ali, James W B Bainbridge
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2010-06-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://doi.org/10.1371/journal.pone.0011103
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