Pyrrole-Based Enaminones as Building Blocks for the Synthesis of Indolizines and Pyrrolo[1,2-<i>a</i>]pyrazines Showing Potent Antifungal Activity

As a new approach, pyrrolo[1,2-<i>a</i>]pyrazines were synthesized through the cyclization of 2-formylpyrrole-based enaminones in the presence of ammonium acetate. The enaminones were prepared with a straightforward method, reacting the corresponding alkyl 2-(2-formyl-1<i>H</i>-pyrrol-1-yl)acetates,...

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Ngā kaituhi matua:	Diter Miranda-Sánchez, Carlos H. Escalante, Dulce Andrade-Pavón, Omar Gómez-García, Edson Barrera, Lourdes Villa-Tanaca, Francisco Delgado, Joaquín Tamariz
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2023-10-01
Rangatū:	Molecules
Ngā marau:	pyrrolo[1,2-<i>a</i>]pyrazines substituted pyrroles enaminones indolizines antifungal activity multidrug-resistant <i>Candida</i> spp.
Urunga tuihono:	https://www.mdpi.com/1420-3049/28/20/7223
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!