Early monitoring of plasma KRAS G12C with digital PCR predicts antitumor response to immunotherapy or sotorasib in advanced NSCLC: A brief report

Background: The frontline management of non-oncogene addicted non-small cell lung cancer (NSCLC) involves immune-checkpoint inhibitors (ICI) alone or combined with chemotherapy (CT-ICI). The dynamic landscape of KRAS-positive NSCLC presents a spectrum of treatment options, including ICIs, targeted t...

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Principais autores:	Andrea De Giglio, Federico Zacchini, Giulia Venturi, Alessandro Di Federico, Claudia Parisi, Filippo Gustavo Dall’Olio, Ilaria Ricciotti, Valentina Favorito, Ambrogio Gagliano, Dario De Biase, Thais Maloberti, Annalisa Altimari, Elisa Gruppioni, Giovanni Tallini, Barbara Melotti, Francesca Sperandi, Francesco Gelsomino, Lorenzo Montanaro, Andrea Ardizzoni
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-12-01
叢編:	The Journal of Liquid Biopsy
主題:	Non-small cell lung cancer Liquid biopsy Immunotherapy Kras
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2950195424000262
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