Ubiquitin-specific protease 15 interacts directly with the HSV-1 alkaline nuclease and facilitates viral recombination and replication fork stability

ABSTRACT Herpes simplex virus type 1 replicates in the nucleus of the host cell and utilizes many cellular proteins to facilitate DNA replication. HSV-1 DNA replication is closely linked with homologous recombination, and HSV-1 encodes a two-subunit recombinase consisting of an exonuclease (UL12) an...

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Egile Nagusiak:	Yee Vue, Patrick J. Mullon, Alexander Leehangin, Emiliano Maldonado-Luevano, Tyler D. Hasselmann, Kavi P. M. Mehta, Kareem N. Mohni
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology 2025-09-01
Saila:	Journal of Virology
Gaiak:	herpes simplex virus DNA replication DNA repair iPOND alkaline nuclease
Sarrera elektronikoa:	https://journals.asm.org/doi/10.1128/jvi.00893-25
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